CAD (Primary)

CAD (Primary) is when Cold Agglutinin issues have no notable or testable secondary cause such as underlying active Lymphoma and various other triggers.

CAD (Secondary) is when Cold Agglutinin has a known testable cause such as having active Lymphoma or other various Triggers.  In 2021 we have starting seeing Secondary CAD also referred to as CAS (Cold Agglutinin Syndrome)

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