CAD verses CAS

CAD in the case of our subject is the acronym for “Cold Agglutinin Disease“.
Thought of as “Primary” Cold Agglutinin.

CAS in the the case of our subject is the acronym for “Cold Agglutinin Syndrome
Thought of as “Secondary” Cold Agglutinin

We wish to document this.  To keep our subscribers  and members up to speed.  Over the years we have often heard of “Primary” Cold Agglutinin and “Secondary” Cold Agglutinin.   In some more recent search through medical research papers (2021) we are starting to see the acronym of CAS surface and being used interchangeably with Secondary CAD.

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