Cold Agglutinin Disease (CAD) is a rare autoimmune blood disease.  Where Cold sensitive or cold triggered antibodies, attack ones own Red Blood Cells causing them to be destroyed.

More in depth, Cold Agglutinin Disease is a rare type of Autoimmune Hemolytic Anemia.  A disease that causes the body’s own Immune System to attack and destroy its own Red Blood Cells.  This destruction of Red Blood Cells is accelerated when an affected person’s body or blood, is exposed to cooler or cold temperatures. Somewhat less than 37°C/98.6°F.

In addition to temperature being a prime concern for a CAD.  Affected people tend to have a lower immune system in general.  Their Red Blood Counts (Production & Destruction) are further impacted by other common viruses, as well as by abnormal levels of Iron and/or Vitamin B12.

While Cold Agglutinin Disease can be passing in nature, or temporary.  It can also be long term or a life long disease that affects ones lifestyle or quality of life.  Cold Agglutinin Disease can be considered Primary or Secondary.

See: Autoimmune Hemolytic Anemia

See: I was just informed I have Cold Agglutinin Disease – Now what?

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